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Clin Chim Acta. 2012 Jan 18;413(1-2):48-65. doi: 10.1016/j.cca.2011.09.037. Epub 2011 Oct 18.

hCG, five independent molecules.

Author information

1
USA hCG Reference Service Reference Service, Division of Women's Health Research, Albuquerque, NM 87104, United States. larry@hcglab.com

Abstract

INTRODUCTION:

The hCG amino acid sequence supports 5 glycoproteins. All are called hCG forms. This review examines all 5 molecules, the hormone as produced by the placental syncytiotrophoblast cells, the sulfated hormone produced by the pituitary gonadotrope cells, the hyperglycosylated hCG autocrine made by placental cytotrophoblast cells, and the autocrine cancer promoters hyperglycosylated hCG, hCGß and hyperglycosylated hCGß as made by all malignancies. This review examines all the molecules and multiple proven functions, ranging from evolution to cancer promotion to hormone action.

RESULTS AND DISCUSSION:

hCG forms are critical super-growth factors in humans, with an exceptional wide range of functions.

PMID:
22027338
DOI:
10.1016/j.cca.2011.09.037
[Indexed for MEDLINE]

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