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Acta Paediatr. 2012 Mar;101(3):264-70. doi: 10.1111/j.1651-2227.2011.02504.x. Epub 2011 Nov 22.

Prediction of outcome at 5 years from assessments at 2 years among extremely preterm children: a Norwegian national cohort study.

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Department of Clinical Medicine, University of Bergen, Norway.



To examine the predictive value of early assessments on developmental outcome at 5 years in children born extremely preterm.


This is a prospective observational study of all infants born in Norway in 1999-2000 with gestational age (GA) <28 weeks or birth weight (BW) <1000 g. At 2 years of age, paediatricians assessed mental and motor development from milestones. At 5 years, parents completed questionnaires on development and professional support before cognitive function was assessed with Wechsler Preschool and Primary Scale of Intelligence-Revised (WPPSI-R) and motor function with the Movement Assessment Battery for children (ABC test).


Twenty-six of 373 (7%) children had cerebral palsy at 2 and 29 of 306 (9%) children at 5 years. Of children without major impairments, 51% (95% CI 35-67) of those with and 22% (95% CI 16-28) without mental delay at 2 years had IQ <85 at 5 years, and 36% (95% CI 20-53 with and 16% (95% CI 11-21) without motor delay at 2 years had an ABC score >95th percentile (poor function). Approximately half of those without major impairments but IQ <85 or ABC score >95th percentile had received support or follow-up beyond routine primary care.


Previous assessments had limited value in predicting cognitive and motor function at 5 years in these extremely preterm children without major impairments.

[Indexed for MEDLINE]

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