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Curr Opin Immunol. 2011 Dec;23(6):778-83. doi: 10.1016/j.coi.2011.09.007. Epub 2011 Oct 19.

Advances in atopic dermatitis.

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1
Department of Dermatology and Allergy, University of Bonn, Sigmund-Freud Str. 25, D-53105 Bonn, Germany.

Abstract

Atopic dermatitis (AD) results from barrier defects combined with modified immune responses of the innate and the adaptive immune system to exogenous and endogenous factors. Recent research has continued to sort out the complex pathophysiologic puzzle of this frequent skin disease. However, the network of mechanisms leading to the manifestation of AD is far from being completely understood.

PMID:
22018455
PMCID:
PMC3232325
DOI:
10.1016/j.coi.2011.09.007
[Indexed for MEDLINE]
Free PMC Article
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