Format

Send to

Choose Destination
Obstet Gynecol. 2011 Nov;118(5):1157-63. doi: 10.1097/AOG.0b013e31823403f4.

Fetal and neonatal alloimmune thrombocytopenia: a management algorithm based on risk stratification.

Author information

1
Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-0587, USA. ldpachec@utmb.edu

Abstract

Fetal and neonatal alloimmune thrombocytopenia constitutes the most common cause of severe thrombocytopenia in fetuses and neonates and of intracranial hemorrhage among term newborns. The cornerstone of therapy involves the use of steroids and intravenous immunoglobulins. Despite the risk of potentially devastating consequences to the fetus, fetal blood sampling has typically been used to document response to therapy. We propose a therapeutic algorithm based on risk stratification with individualized treatment optimization without the use of fetal blood sampling.

PMID:
22015886
DOI:
10.1097/AOG.0b013e31823403f4
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wolters Kluwer
Loading ...
Support Center