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Epilepsy Behav. 2011 Dec;22(4):793-5. doi: 10.1016/j.yebeh.2011.09.003. Epub 2011 Oct 20.

Accelerated long-term forgetting in temporal lobe epilepsy: evidence of improvement after left temporal pole lobectomy.

Author information

1
Department of Neurological Sciences, University of Bologna, Bologna, Italy. roberto.gallassi@unibo.it

Abstract

Accelerated long term forgetting (ALF) is a characteristic cognitive aspect in patients affected by temporal lobe epilepsy that is probably due to an impairment of memory consolidation and retrieval caused by epileptic activity in hippocampal and parahippocampal regions. We describe a case of a patient with TLE who showed improvement in ALF and in remote memory impairment after an anterior left temporal pole lobectomy including the uncus and amygdala. Our findings confirm that impairment of hippocampal functioning leads to pathological ALF, whereas restoration of hippocampal functioning brings ALF to a level comparable to that of controls.

PMID:
22015212
DOI:
10.1016/j.yebeh.2011.09.003
[Indexed for MEDLINE]

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