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Physiology (Bethesda). 2011 Oct;26(5):348-64. doi: 10.1152/physiol.00017.2011.

COPII and COPI traffic at the ER-Golgi interface.

Author information

1
Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Abstract

Protein traffic is necessary to maintain homeostasis in all eukaryotic organisms. All newly synthesized secretory proteins destined to the secretory and endolysosmal systems are transported from the endoplasmic reticulum to the Golgi before delivery to their final destinations. Here, we describe the COPII and COPI coating machineries that generate carrier vesicles and the tethers and SNAREs that mediate COPII and COPI vesicle fusion at the ER-Golgi interface.

PMID:
22013193
DOI:
10.1152/physiol.00017.2011
[Indexed for MEDLINE]
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