Send to

Choose Destination
See comment in PubMed Commons below
Ann Biol Clin (Paris). 2011 Sep-Oct;69(5):523-9. doi: 10.1684/abc.2011.0610.

[The changing epidemiology of extended spectrum β-lactamase-producing Klebsiella pneumoniae].

[Article in French]

Author information

  • 1Faculté de Pharmacie, Laboratoire des Maladies Transmissibles etSubstances Biologiquement Actives, LR99ES27, Monastir, Tunisie.


In the last two decades, Klebsiella pneumoniae demonstrated some characteristics of acquisition of plasmids coding extended spectrum β-lactamases (ESBL). The review data showed an increase in worldwide prevalence of ESBL and a temporal shift in the prevalence of ESBL types in K. pneumoniae during this last decade. CTX-M-15 seems to be the predominant ESBL type in K. pneumoniae in some parts of the world. The dissemination of several nosocomial CTX-M-15-producing K. pneumoniae clones was reported unlike the worldwide dissemination of a single virulent ST131 CTX-M-15 producing Escherichia coli clone. The diversity of plasmids carrying the bla(CTX-M-15) gene in K. pneumoniae suggested the frequent transfer of this gene between different replicons. The acquisition of the bla(CTX-M-15) gene by K. pneumoniae was probably occurred via horizontal transfer from E. coli.

[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for John Libbey Eurotext
    Loading ...
    Support Center