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Respir Care. 2012 Mar;57(3):444-8. doi: 10.4187/respcare.01373. Epub 2011 Oct 12.

Inhaled nitric oxide as salvage therapy in massive pulmonary embolism: a case series.

Author information

1
Eastern Virginia Medical School, Norfolk, VA, USA.

Abstract

Inhaled nitric oxide (INO) has been shown to preferentially lower resistance in the pulmonary vasculature. The relative selectiveness of INO in accomplishing this effect makes it an attractive drug to administer as salvage therapy in patients with acute right ventricular failure secondary to pulmonary embolism. We describe 4 cases in which INO was used as a temporizing agent to decrease right ventricular after-load following massive near-fatal pulmonary embolism. All 4 patients survived to hospital discharge.

PMID:
22005573
DOI:
10.4187/respcare.01373
[Indexed for MEDLINE]
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