Format

Send to

Choose Destination
J Magn Reson Imaging. 2012 Jan;35(1):95-102. doi: 10.1002/jmri.22728. Epub 2011 Oct 14.

Characterization of adrenal lesions using chemical shift MRI: comparison between 1.5 Tesla and two echo time pair selection at 3.0 Tesla MRI.

Author information

1
Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Abstract

PURPOSE:

To compare chemical shift MRI obtained at 1.5 Tesla (T) and two pairs of echo time (TE) in-phase and opposed-phase 3.0T MRI to assess their usefulness for the differentiation between adrenal adenomas and non-adenomas.

MATERIALS AND METHODS:

We evaluated 91 adrenal masses (75 adenomas, 16 non-adenomas) in 85 patients. The MR imaging parameters were: T1-dual-gradient-echo(GRE) [echo times (TEs) = 1.1/2.3 ms (first-echo-pair) or 3.5/4.6 ms (second-echo-pair)] at 3.0T, and T1-dual-GRE (TEs = 2.4/4.8 ms) at 1.5T. Scans were quantitatively assessed for the signal intensity (SI) index, calculated as [(SIin-phase-SIopposed-phase)/(SIin-phase)] × 100(%). To test for differences between adenomas and non-adenomas, we performed quantitative analysis and analysis of variance.

RESULTS:

For all images, the SI index differed significantly between adenomas and non-adenomas. The sensitivity /specificity of SI index at the first-echo-pair of 3.0T was 100%/ 100%, that of 95.6%/ 100% at the second-echo-pair of 3.0T, and 91.7%/ 88.9% at 1.5T, respectively. At intra-individual comparisons, the SI indices obtained with the second-echo-pair at 3.0T were significantly lower than on the first-echo-pair at 3.0T and 1.5T.

CONCLUSION:

Chemical shift MRI at 3.0T provides more accurate differentiation between adenomas and non-adenomas than at 1.5T. The SI index of the first-echo-pair at 3.0T is the most reliable evaluation method for differentiating adrenal adenomas from non-adenomas.

PMID:
22002867
DOI:
10.1002/jmri.22728
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center