Format

Send to

Choose Destination
Expert Rev Vaccines. 2011 Oct;10(10):1389-92. doi: 10.1586/erv.11.106.

Mucosal immunity to poliovirus.

Author information

1
State University of New York, Women and Children's Hospital, 219 Bryant Street, Buffalo, NY 14222, USA.

Abstract

The Global Polio Eradication Initiative (GPEI) currently based on use of oral poliovirus vaccine (OPV) has identified suboptimal immunogenicity of this vaccine as a major impediment to eradication, with a failure to induce protection against paralytic poliomyelitis in certain population segments in some parts of the world. The Mucosal Immunity and Poliovirus Vaccines: Impact on Wild Poliovirus Infection, Transmission and Vaccine Failure conference was organized to obtain a better understanding of the current status of global control of poliomyelitis and identify approaches to improve the immune responsiveness and effectiveness of the orally administered poliovirus vaccines in order to accelerate the global eradication of paralytic poliomyelitis.

PMID:
21988303
DOI:
10.1586/erv.11.106
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center