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Caries Res. 2011;45(6):518-23. doi: 10.1159/000331391. Epub 2011 Oct 5.

Reduction of erosive wear in situ by stannous fluoride-containing toothpaste.

Author information

1
College of Dental Science, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. m.c.d.n.j.m.huysmans@dent.umcn.nl

Abstract

BACKGROUND/AIMS:

Stannous fluoride (SnF) has been suggested as a dental erosion-preventive agent. The aim of this single-centre, randomized, double-blind, in situ study was to evaluate the effect of toothpastes with SnF in the prevention of erosive enamel wear.

METHODS:

A combined split-mouth (extra-oral water or toothpaste brushing) and crossover (type of toothpaste) set-up was used. Twelve volunteers wore palatal appliances containing human enamel samples. Three toothpastes were used, in three consecutive runs, in randomized order: two toothpastes containing SnF (coded M and PE) and one toothpaste containing only sodium fluoride (coded C). On day 1 of each run the appliances were worn for pellicle formation. On days 2-5 the samples were also brushed twice with a toothpaste-water slurry or only water (control). Erosion took place on days 2-5 extra-orally 3 times a day (5 min) in a citric acid solution (pH 2.3). Enamel wear depth was quantified by optical profilometry. The effect of toothpastes was tested using General Linear Modeling.

RESULTS:

Average erosive wear depth of control samples was 23 μm. Both SnF toothpastes significantly reduced erosive wear: M by 34% (SD 39%) and PE by 26% (SD 25%). The control toothpaste reduced erosive wear non-significantly by 7% (SD 20%). Both SnF-containing toothpastes significantly reduced erosive wear compared to the sodium fluoride toothpaste.

CONCLUSION:

We conclude that SnF-containing toothpastes are able to reduce erosive tooth wear in situ.

PMID:
21985895
DOI:
10.1159/000331391
[Indexed for MEDLINE]

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