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Res Vet Sci. 2012 Oct;93(2):795-7. doi: 10.1016/j.rvsc.2011.09.013. Epub 2011 Oct 7.

Reduction of ochratoxin A in broiler serum and tissues by Trichosporon mycotoxinivorans.

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Department of Biochemistry, PMAS-Arid Agriculture University, Rawalpindi, Pakistan.


The present study was planned to evaluate the possible transmission of ochratoxin A (OTA) in serum and targeted organs of broilers fed on two levels (500 and 1000 ppb) this toxin in the presence or absence of a toxin deactivator (containing a mycotoxin deactivating yeast Trichosporon mycotoxinivorans) at two inclusion levels (1 and 2 kg/ton of feed) to 270 day-old broiler chicks divided into nine groups (A-I) over a 42 days period. Serum samples were collected at 14, 28 and 42nd day of experiment, whereas, liver and kidney tissues were obtained from broilers slaughtered at 42nd day of experiment. The highest OTA levels were detected in serum, livers and kidneys of OTA treated groups without supplementation of toxin deactivator (groups D and G) at day 42 of experiment, while the residues were significantly (P<0.01) lower in treatment groups (F and I) supplemented with toxin deactivator at 2 kg/ton of feed. The order of OTA level was serum>kidneys>liver.

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