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Neuron. 2011 Oct 6;72(1):3-5. doi: 10.1016/j.neuron.2011.09.017.

MeCP2: phosphorylated locally, acting globally.

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1
Department of Biology and National Center for Behavioral Genomics, Brandeis University, Waltham, MA 02454, USA.

Abstract

In this issue of Neuron, Greenberg and colleagues revise our understanding of how activity-dependent MeCP2 phosphorylation regulates distinct aspects of brain development and circuit function. The study also suggests a prominent role for MeCP2 in the regulation of global chromatin state in vivo.

PMID:
21982363
DOI:
10.1016/j.neuron.2011.09.017
[Indexed for MEDLINE]
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