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Otolaryngol Clin North Am. 2011 Oct;44(5):1155-71. doi: 10.1016/j.otc.2011.06.002. Epub 2011 Jul 21.

Skull base chordomas.

Author information

1
Department of Neurological Surgery, University of Pittsburgh School of Medicine, 200 Lothrop Street, PUH 400, Pittsburgh, PA 15213, USA.

Abstract

Skull base chordomas are rare midline malignancies of clival origin that represent one of the most challenging skull base tumors to treat, given their location, invasiveness, potential extension around vital neurovascular structures, and high recurrence rate. Total tumor resection is the mainstay of treatment. The combination of surgery and postoperative irradiation appears to provide the best outcome.

PMID:
21978899
DOI:
10.1016/j.otc.2011.06.002
[Indexed for MEDLINE]

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