Send to

Choose Destination
See comment in PubMed Commons below
Schizophr Bull. 1990;16(2):255-61.

Implications of olfactory agnosia for understanding sex differences in schizophrenia.

Author information

Dept. of Psychiatry, University of British Columbia, Vancouver, Canada.


In our studies, 50 percent of the male patients with schizophrenia have an olfactory agnosia. This finding is of interest because the olfactory neuroanatomical network involves brain regions found to be abnormal in patients with schizophrenia, and this olfactory deficit appears to be sex dependent. This article reviews conceptual models for assessing olfactory function, describes the neuroanatomical structures involved, and reviews the findings of olfactory performance in patients with neurological dysfunction. The findings are then integrated with neuropathological studies of patients with schizophrenia. Finally, as there is increasing evidence for a sex difference in patients with schizophrenia, a model is suggested to account for these differences based on neuro-developmental and latent lesion hypotheses.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center