Format

Send to

Choose Destination
Nat Cell Biol. 2011 Oct 3;13(10):1178-82. doi: 10.1038/ncb2348.

A brief history of error.

Author information

1
Harvard University, Molecular and Cellular Biology, 52 Oxford Street, Northwest Science Building, Cambridge, Massachusetts 02138, USA. awm@mcb.harvard.edu

Abstract

The spindle checkpoint monitors chromosome alignment on the mitotic and meiotic spindle. When the checkpoint detects errors, it arrests progress of the cell cycle while it attempts to correct the mistakes. This perspective will present a brief history summarizing what we know about the checkpoint, and a list of questions we must answer before we understand it.

PMID:
21968991
DOI:
10.1038/ncb2348
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center