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Biol Psychol. 2012 Jan;89(1):269-72. doi: 10.1016/j.biopsycho.2011.09.012. Epub 2011 Oct 1.

Preliminary evidence that acute long-chain omega-3 supplementation reduces cardiovascular reactivity to mental stress: a randomized and placebo controlled trial.

Author information

1
Department of Psychology and Neuroscience Program, Allegheny College, Meadville, PA 16335, USA. axg937@bham.ac.uk

Abstract

OBJECTIVE:

Exaggerated cardiovascular reactivity predicts cardiovascular morbidity and mortality. Some evidence suggests that omega-3 fatty acids improve cardiovascular function. The objective of this study was to examine the influence of an acute low dose of long-chain omega-3 fatty acids on young, healthy individuals.

METHODS:

Participants (n=34) were randomly assigned to either 21-days of omega-3 fatty acids (1.4 g EPA and DHA) or matched placebo. Cardiovascular measurements were obtained in the laboratory during baseline and during a standard mental arithmetic task, where participants were instructed to engage in serial subtractions by 17s from a four-digit number and cardiovascular reactivity to the task was calculated.

RESULTS:

Mean arterial pressure reactivity was significantly reduced by supplementation (F(1,32)=5. 12, p=.03, η(2)=.144) but not by placebo.

CONCLUSION:

Supplementation of omega-3 fatty acids may reduce cardiovascular reactivity to stress.

PMID:
21967854
DOI:
10.1016/j.biopsycho.2011.09.012
[Indexed for MEDLINE]

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