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Bioinformatics. 2011 Dec 1;27(23):3317-8. doi: 10.1093/bioinformatics/btr548. Epub 2011 Oct 3.

ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression.

Author information

1
Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.

Abstract

SUMMARY:

We introduce ProfileChaser, a web server that allows for querying the Gene Expression Omnibus based on genome-wide patterns of differential expression. Using a novel, content-based approach, ProfileChaser retrieves expression profiles that match the differentially regulated transcriptional programs in a user-supplied experiment. This analysis identifies statistical links to similar expression experiments from the vast array of publicly available data on diseases, drugs, phenotypes and other experimental conditions.

AVAILABILITY:

http://profilechaser.stanford.edu

CONTACT:

abutte@stanford.edu

SUPPLEMENTARY INFORMATION:

Supplementary data are available at Bioinformatics online.

PMID:
21967760
PMCID:
PMC3223361
DOI:
10.1093/bioinformatics/btr548
[Indexed for MEDLINE]
Free PMC Article
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