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Essays Biochem. 2011 Sep 7;50(1):85-99. doi: 10.1042/bse0500085.

ABC solute importers in bacteria.

Author information

1
Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907, U.S.A.

Abstract

The bacterial ABC (ATP-binding cassette) importers mediate nutrient uptake and some are essential for survival in environments where nutrients are limited, such as in the human body. Although ABC importers exhibit remarkable versatility in the substrates that they can transport, they appear to share a similar multisubunit architecture and mechanism of energization by ATP hydrolysis. This chapter will provide both basic understanding and up-to-date information on the structure, mechanism and regulation of this important family of proteins.

PMID:
21967053
DOI:
10.1042/bse0500085
[Indexed for MEDLINE]

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