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AJNR Am J Neuroradiol. 2012 Jun;33(6):E82-4. doi: 10.3174/ajnr.A2701. Epub 2011 Sep 29.

Multimodal imaging of spike propagation: a technical case report.

Author information

1
Athinoula A. Martinos Center for Biomedical Imaging,, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA. naoro@nmr.mgh.harvard.ed

Abstract

We report an 11-year-old boy with intractable epilepsy, who had cortical dysplasia in the right superior frontal gyrus. Spatiotemporal source analysis of MEG and EEG spikes demonstrated a similar time course of spike propagation from the superior to inferior frontal gyri, as observed on intracranial EEG. The tractography reconstructed from DTI showed a fiber connection between these areas. Our multimodal approach demonstrates spike propagation and a white matter tract guiding the propagation.

PMID:
21960488
PMCID:
PMC3612946
DOI:
10.3174/ajnr.A2701
[Indexed for MEDLINE]
Free PMC Article
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