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Diagn Interv Radiol. 2012 Jan-Feb;18(1):60-6. doi: 10.4261/1305-3825.DIR.3994-10.1. Epub 2011 Sep 29.

Diffusion tensor imaging in carpal tunnel syndrome.

Author information

1
Department of Radiology, Yeditepe University School of Medicine, İstanbul, Turkey. ntasdelen@yeditepe.edu.tr

Abstract

PURPOSE:

We aimed to investigate the efficacy of diffusion tensor imaging in the diagnosis of carpal tunnel syndrome and to obtain a quantitative parameter that may contribute to the diagnosis.

MATERIALS AND METHODS:

The median nerves in 57 wrists of 38 patients diagnosed as carpal tunnel syndrome and 30 wrists of 24 normal subjects were prospectively evaluated with a 3T Philips scanner, using standard 8-channel SENSE head coil. Diffusion tensor imaging was performed using spin echo-echo planar imaging. For anatomical reference, a T1-weighted sequence was acquired. Fractional anisotropy and apparent diffusion coefficient measurements were done focally at the carpal tunnel level and from whole median nerve.

RESULTS:

In carpal tunnel syndrome patients, both focal carpal tunnel and whole nerve measurements demonstrated statistically significantly lower fractional anisotropy values than normal subjects (P < 0.001). No statistically significant difference was observed in apparent diffusion coefficient measurements. The cut-off value obtained by receiver operator characteristics analysis was 0.554 for focal carpal tunnel fractional anisotropy (sensitivity, 80%; specificity, 80%) and 0.660 for whole nerve fractional anisotropy (sensitivity, 82%; specificity, 80%) measurement.

CONCLUSION:

Diffusion tensor imaging may contribute to the diagnosis of carpal tunnel syndrome on the basis of fractional anisotropy measurements.

PMID:
21960133
DOI:
10.4261/1305-3825.DIR.3994-10.1
[Indexed for MEDLINE]
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