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Curr Biol. 2011 Sep 27;21(18):R697-9. doi: 10.1016/j.cub.2011.08.017.

Autophagy: cells SNARE selves.

Author information

1
Department of Molecular Physiology and Biological Physics and Center for Membrane Biology, University of Virginia, Charlottesville, VA, USA. chris.stroupe@virginia.edu

Abstract

Autophagosomes sequester cytosolic constituents and deliver this cargo to lysosomes for destruction. Two groups now report that autophagosome maturation requires homotypic membrane fusion catalyzed by SNARE proteins.

PMID:
21959158
DOI:
10.1016/j.cub.2011.08.017
[Indexed for MEDLINE]
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