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Chem Commun (Camb). 2011 Nov 7;47(41):11534-6. doi: 10.1039/c1cc14437e. Epub 2011 Sep 26.

An aryl-phosphonate appended macrocyclic platform for lanthanide based bimodal imaging agents.

Author information

1
Department for Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Spemannstr. 38, 72076 Tübingen, Germany.

Abstract

Four ligand systems have been prepared whose characteristics are well suited to the design of bimodal MRI and luminescence probes. The lanthanide complexes display high relaxivities and luminescence quantum yields. These properties are retained at higher magnetic fields and in a range of competitive environments including model extracellular medium and cultured cells.

PMID:
21952162
DOI:
10.1039/c1cc14437e
[Indexed for MEDLINE]

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