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Mycopathologia. 2012 Jun;173(5-6):303-10. doi: 10.1007/s11046-011-9473-z. Epub 2011 Sep 24.

Ten challenges on Cryptococcus and cryptococcosis.

Author information

1
Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA. delpoeta@musc.edu

Abstract

Cryptococcosis has become a significant public global health problem worldwide. Caused by two species, Cryptococcus neoformans or Cryptococcus gattii, this life-threatening infection afflicts not only immunocompromised individuals but also apparently immunocompetent subjects. Hence, cryptococcosis should no longer be considered merely an opportunistic infection. In this article, we focus on ten unanswered questions/topics in this field with the hope to stimulate discussion and research on these topics that would lead not only to a better understanding of the physiopathology of this disease but also to a better diagnosis and prognosis.

PMID:
21948062
PMCID:
PMC4294698
DOI:
10.1007/s11046-011-9473-z
[Indexed for MEDLINE]
Free PMC Article

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