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Epilepsy Res. 2012 Feb;98(2-3):251-4. doi: 10.1016/j.eplepsyres.2011.09.001. Epub 2011 Sep 25.

Diffusion tensor imaging of subependymal heterotopia.

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Department of Neuroscience and Imaging, University G. D'Annunzio, Chieti, Italy.


A magnetic resonance (MR) diffusion tensor imaging (DTI) study was performed in a newborn with bilateral subependymal heterotopia (SE). White matter fractional anisotropy (FA), axial diffusivity (AD) and radial diffusivity (RD) were compared to values obtained in four newborns with moderate perinatal asphyxia and normal MRI findings. The reduction of FA and increase of AD and RD in the newborn with SE were the in vivo late expression of alterations in the intermediate zone, with an underlying arrest of neuronal migration.

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