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Hepatogastroenterology. 2012 Jan-Feb;59(113):292-5. doi: 10.5754/hge11399.

Risk factors of ascites after hepatectomy for patients with hepatocellular carcinoma and hepatitis B virus-associated cirrhosis.

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1
Sichuan University, Chengdu, China.

Abstract

BACKGROUND/AIMS:

To identify risk factors of postoperative ascites after hepatectomy for patients with hepatocellular carcinoma (HCC) and hepatitis B virus associated-cirrhosis.

METHODOLOGY:

The data of 73 patients were reviewed in current study. Pre- and intra-operative variables were retrospectively analyzed using uni- and multi-variate analyses. The diagnostic accuracy of the predictors was evaluated by the receiver operating characteristics (ROC) analysis.

RESULTS:

Indocyanine green retention rate at 15 minutes (ICGR15) >10%, tumor size >10cm, splenectomy, middle hepatic vein (MHV) resection, red blood cell (RBC) transfusion were risk factors in univariate analysis. However, only ICGR15 >10%, tumor size >10cm and RBC transfusion showed prognostic power in multivariate analysis. ROC analysis suggested the best cut-off value of risk factors was 2.

CONCLUSIONS:

Our study indicated the postoperative ascites could be predicted by pre- and intra-operative variables. ICGR15 >10%, tumor size >10cm and RBC transfusion were independent risk factors for ascites after hepatectomy. Patients with two or more of the above-mentioned risk factors may suffer postoperative ascites after hepatectomy.

PMID:
21940357
DOI:
10.5754/hge11399
[Indexed for MEDLINE]

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