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Trends Biochem Sci. 1990 May;15(5):195-8.

Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells.

Author information

1
Friedrich-Miescher-Laboratory, Max-Planck-Society, Tübingen, FRG.

Abstract

Covalent attachment of ubiquitin to cellular proteins is essential for cell viability and is catalysed by a set of distinct ubiquitin-conjugating enzymes. Individual members of this novel enzyme family mediate strikingly diverse functions, including DNA repair, cell cycle control, selective protein degradation and essential functions of the stress response.

PMID:
2193438
[Indexed for MEDLINE]

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