Format

Send to

Choose Destination
J Infect Dis. 2011 Nov 15;204(10):1523-6. doi: 10.1093/infdis/jir614. Epub 2011 Sep 16.

Seroepidemiology of the newly found trichodysplasia spinulosa-associated polyomavirus.

Author information

1
Department of Virology, Haartman Institute, Finland.

Abstract

Trichodysplasia spinulosa (TS)-associated polyomavirus (TSV) was recently (in 2010) discovered in TS lesions. To investigate the seroprevalence and primary exposure time of this virus, we set up a virus protein (VP1) viruslike particle (VLP)-based immunoglobulin G enzyme immunoassay. The seroprevalence of TSV was 5%, among children aged 1-4 years, rising to 48% at 6-10 years, and 70% among 149 adults. The TSV antibodies did not cross-react with corresponding Merkel cell polyomavirus VLPs, and their reactivity appeared conformational. TSV circulates widely in the human population and primary exposure is extensive in childhood, beginning at age 1-2 years.

PMID:
21926381
DOI:
10.1093/infdis/jir614
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center