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Dermatol Clin. 2011 Oct;29(4):555-9. doi: 10.1016/j.det.2011.06.012. Epub 2011 Aug 6.

Mycophenolate mofetil for the management of autoimmune bullous diseases.

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Department of Dermatology, Rabin Medical Center, Beilinson Campus, Jabotinski Street 39, Petah Tiqwa 49100, Israel.


Immunosuppressive agents such as azathioprine, cyclophosphamide, and mycophenolate mofetil (MMF) are now widely used in the treatment of autoimmune bullous diseases. This article reviews the use of MMF for the treatment of several bullous conditions, and assesses the evidence gathered from clinical trials and case series. According to numerous case series, MMF could be of value in treating refractory disease. The few randomized clinical trials conducted to date of patients with pemphigus and bullous pemphigoid report a similar efficacy for MMF to other immunosuppressants.

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