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J Neurosurg. 2012 Jan;116(1):95-8. doi: 10.3171/2011.8.JNS101552. Epub 2011 Sep 16.

Combined pallidal and subthalamic nucleus stimulation in sporadic dystonia-parkinsonism.

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1
Department of Neurology, University Hospital Mannheim, Germany.

Abstract

Multifocal deep brain stimulation (DBS) is a new technique that has been introduced recently. A 39-year-old man with dystonia-parkinsonism underwent the simultaneous implantation of subthalamic nucleus (STN) and globus pallidus internus (GPi) DBS electrodes. While bilateral STN DBS controlled the parkinsonian symptoms well and allowed for a reduction in levodopa, the improvement of dystonia was only temporary. Additional GPi DBS also alleviated dystonic symptoms. Formal assessment at the 1-year follow-up showed that both the parkinsonian symptoms and the dystonia were markedly improved via continuous bilateral combined STN and GPi stimulation. Sustained benefit was achieved at 3 years postoperatively.

PMID:
21923241
DOI:
10.3171/2011.8.JNS101552
[Indexed for MEDLINE]
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