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Virulence. 2011 Sep-Oct;2(5):445-59. doi: 10.4161/viru.2.5.17724. Epub 2011 Sep 1.

Staphylococcus aureus biofilms: properties, regulation, and roles in human disease.

Author information

1
Department of Microbial Pathogenesis, Dental School, University of Maryland, Baltimore, MD, USA.

Abstract

Increasing attention has been focused on understanding bacterial biofilms and this growth modality's relation to human disease. In this review we explore the genetic regulation and molecular components involved in biofilm formation and maturation in the context of the Gram-positive cocci, Staphylococcus aureus. In addition, we discuss diseases and host immune responses, along with current therapies associated with S. aureus biofilm infections and prevention strategies.

PMID:
21921685
PMCID:
PMC3322633
DOI:
10.4161/viru.2.5.17724
[Indexed for MEDLINE]
Free PMC Article

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