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Clin Med Insights Oncol. 2011;5:259-64. doi: 10.4137/CMO.S7871. Epub 2011 Aug 23.

A study of aspects on gender and prognosis in synchronous colorectal cancer.

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Sahlgrenska Academy, Department of Surgery, Sahlgrenska University Hospital, Ă–stra 41685 Gothenburg, Sweden.



To assess differences in demography, pathology and prognosis with tumor multiplicity in colorectal cancer.


A retrospective single centre study of all patients surgically treated for a colorectal cancer during 1999-2008 (n = 2524). Patient characteristics, pathology and follow-up data were retrieved. Survival was assessed by overall and cancer specific survival.


60 (2.4%) patients had a synchronous cancer (SC), associated with right colon, higher age, more assessed lymph nodes but a lower frequency of stage III/IV disease (42% vs. 52%). There was no overall prognostic difference between single or multiple cancer patients but females with SC had better survival than corresponding males (P < 0.046).


The incidence of synchronous cancers was 2.4% with the second cancer often located in right colon. The SC patients were older than single tumor patients, had a lower frequency of stage III/IV disease and the females with SC had a better survival prognosis than corresponding males.


colorectal cancer; gender; mortality; multiple tumors; survival

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