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Arch Gynecol Obstet. 2012 Apr;285(4):1153-6. doi: 10.1007/s00404-011-2018-3. Epub 2011 Sep 9.

Submental lymph node metastasis from invasive ductal breast carcinoma.

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Department of Plastic Surgery, St. Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK.


This case report presents a 52-year-old woman with a submental swelling which arose 3 years after wide local excision and axillary lymphadenectomy for breast carcinoma. Histopathological examination after excision biopsy of this lesion confirmed the presence of invasive breast carcinoma in a submental lymph node. Computed tomography of the head, neck, thorax, abdomen and pelvis demonstrated multiple brain and pulmonary metastases. Further management was palliative and the patient died 5 months later. This is the first description of a breast carcinoma metastasising to the submental region. Metastatic breast carcinoma should be considered in the differential diagnosis of head and neck lymphadenopathy in patients with previously diagnosed breast carcinoma.

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