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MBio. 2011 Sep 6;2(5). pii: e00141-11. doi: 10.1128/mBio.00141-11. Print 2011.

Antimicrobial actions of reactive oxygen species.

Author information

1
Department of Laboratory Medicine and Microbiology, University of Washington School of Medicine, Seattle, Washington, USA. fcfang@u.washington.edu

Abstract

Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens. The observable antimicrobial actions of ROS are highly dependent on experimental conditions. This perspective reviews recent controversies regarding ROS in Salmonella-phagocyte interactions and attempts to reconcile conflicting observations from different laboratories.

PMID:
21896680
PMCID:
PMC3171981
DOI:
10.1128/mBio.00141-11
[Indexed for MEDLINE]
Free PMC Article

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