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Br Med Bull. 2011;99:39-51. doi: 10.1093/bmb/ldr030.

The epidemiology of thyroid disease.

Author information

1
Department of Endocrinology, Royal Free Hampstead NHS Trust, Pond Street, London NW3 2QG, UK. mark.vanderpump@nhs.net

Abstract

INTRODUCTION:

Thyroid disorders are prevalent and their manifestations are determined by the dietary iodine availability.

SOURCES OF DATA:

Data from screening large population samples from USA and Europe.

AREAS OF AGREEMENT:

The most common cause of thyroid disorders worldwide is iodine deficiency, leading to goitre formation and hypothyroidism. In iodine-replete areas, most persons with thyroid disorders have autoimmune disease.

AREAS OF CONTROVERSY:

Definition of thyroid disorders, selection criteria used, influence of age and sex, environmental factors and the different techniques used for assessment of thyroid function.

GROWING POINTS:

Increasing incidence of well-differentiated thyroid cancer. Environmental iodine influences the epidemiology of non-malignant thyroid disease.

AREAS TIMELY FOR DEVELOPING RESEARCH:

Iodine supplementation of populations with mild-to-moderate iodine deficiency. An evidence-based strategy for the risk stratification, treatment and follow-up of benign nodular thyroid disease. Is there any benefit in screening adults for thyroid dysfunction?

PMID:
21893493
DOI:
10.1093/bmb/ldr030
[Indexed for MEDLINE]

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