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Nat Cell Biol. 2011 Sep 2;13(9):1011. doi: 10.1038/ncb2325.

What's wrong with correlative experiments?

Author information

1
Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA. Marco_Vilela@hms.harvard.edu

Abstract

Here, we make a case for multivariate measurements in cell biology with minimal perturbation. We discuss how correlative data can identify cause-effect relationships in cellular pathways with potentially greater accuracy than conventional perturbation studies.

PMID:
21892139
DOI:
10.1038/ncb2325
[Indexed for MEDLINE]

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