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Emerg Infect Dis. 2011 Sep;17(9):1664-9. doi: 10.3201/eid1709.101987.

Geographic distribution of endemic fungal infections among older persons, United States.

Author information

1
University of Alabama at Birmingham, Birmingham, AL35294-0006, USA. jbaddley@uab.edu

Abstract

To investigate the epidemiology and geographic distribution of histoplasmosis, coccidioidomycosis, and blastomycosis in older persons in the United States, we evaluated a random 5% sample of national Medicare data from 1999 through 2008. We calculated national, regional, and state-based incidence rates and determined 90-day postdiagnosis mortality rates. We identified 776 cases (357 histoplasmosis, 345 coccidioidomycosis, 74 blastomycosis). Patient mean age was 75.7 years; 55% were male. Histoplasmosis and blastomycosis incidence was highest in the Midwest (6.1 and 1.0 cases/100,000 person-years, respectively); coccidioidomycosis incidence rate was highest in the West (15.2). On the basis of available data, for 86 (11.1%) cases, there was no patient exposure to a traditional disease-endemic area. Knowledge of areas where endemic mycosis incidence is increased may affect diagnostic or prevention measures for older adults at risk.

PMID:
21888792
PMCID:
PMC3322071
DOI:
10.3201/eid1709.101987
[Indexed for MEDLINE]
Free PMC Article

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