Format

Send to

Choose Destination
PLoS One. 2011;6(8):e23175. doi: 10.1371/journal.pone.0023175. Epub 2011 Aug 23.

Working memory training using mental calculation impacts regional gray matter of the frontal and parietal regions.

Author information

1
Smart Ageing International Research Center, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan. takehi@idac.tohoku.ac.jp

Abstract

Training working memory (WM) improves performance on untrained cognitive tasks and alters functional activity. However, WM training's effects on gray matter morphology and a wide range of cognitive tasks are still unknown. We investigated this issue using voxel-based morphometry (VBM), various psychological measures, such as non-trained WM tasks and a creativity task, and intensive adaptive training of WM using mental calculations (IATWMMC), all of which are typical WM tasks. IATWMMC was associated with reduced regional gray matter volume in the bilateral fronto-parietal regions and the left superior temporal gyrus. It improved verbal letter span and complex arithmetic ability, but deteriorated creativity. These results confirm the training-induced plasticity in psychological mechanisms and the plasticity of gray matter structures in regions that have been assumed to be under strong genetic control.

PMID:
21886781
PMCID:
PMC3160301
DOI:
10.1371/journal.pone.0023175
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Public Library of Science Icon for PubMed Central
Loading ...
Support Center