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J Dermatol Case Rep. 2010 Nov 19;4(2):25-7. doi: 10.3315/jdcr.2010.1048.

Multiple eruptive clear cell acanthoma.

Author information

1
Department of Dermatology, University of Brescia, Brescia, Italy.

Abstract

BACKGROUND:

Clear cell acanthoma is a rare solitary benign epidermal tumor of unknown etiology. The disease arises in the middle-age, with no sex predominance. It appears as a single reddish papule or papule-nodule and a peripheral scaling collarette is characteristic. Although solitary lesions are the rule, less than 30 cases of multiple Clear cell acanthoma have been described in the literature to date.

MAIN OBSERVATIONS:

We report an unusual case of a healthy 74-year-old male with multiple clear cell acanthoma on the lower extremities treated successfully with cryotherapy.

CONCLUSIONS:

Despite significant progress in treatment of clear cell acanthoma, cryotherapy, based on liquid nitrogen, remains an important alternative in treating multiple clear cell acanthomas.

KEYWORDS:

clear cell acanthoma; cryotherapy; multiple; tumor

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