Format

Send to

Choose Destination
Curr Opin Rheumatol. 2011 Nov;23(6):574-8. doi: 10.1097/BOR.0b013e32834b53cc.

Inclusion body myositis.

Author information

1
Division of Neuromuscular Disease, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. sagreenberg@partners.org

Abstract

PURPOSE OF REVIEW:

Sporadic inclusion body myositis (sIBM) is a poorly understood immune and degenerative disease of skeletal muscle. Here, current opinion of the nature of this disease is summarized.

RECENT FINDINGS:

Recent findings for sIBM include further characterization of muscle involvement through magnetic resonance imaging, the role of muscle as a host for immune cells, progress in the role of extranuclear TDP-43 in causing cellular injury, and the discovery of a new sIBM autoantibody.

SUMMARY:

sIBM understanding continues to advance, with progress regarding the mechanism of this disease.

PMID:
21885973
DOI:
10.1097/BOR.0b013e32834b53cc
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wolters Kluwer
Loading ...
Support Center