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Antimicrob Agents Chemother. 1990 Apr;34(4):665-7.

Randomized, controlled trial of a 10-day course of amifloxacin versus trimethoprim-sulfamethoxazole in the treatment of acute, uncomplicated urinary tract infection. Amifloxacin Multi-Center Trial Group.

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  • 1University of Colorado Health Science Center, Denver 80262.

Abstract

We conducted a randomized controlled trial of orally administered amifloxacin versus trimethoprimsulfamethoxazole (TMP-SMX) as treatments of acute uncomplicated urinary tract infection in women. Amifloxacin at a dosage of 200 mg twice a day appeared as safe and effective as TMP-SMX, but amifloxacin at 400 mg twice a day tended to cause adverse events more frequently than did TMP-SMX.

PMID:
2188590
PMCID:
PMC171664
[PubMed - indexed for MEDLINE]
Free PMC Article
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