In this issue of Molecular Cell, Molin et al. (2011) reveal that caloric restriction alleviates PKA-dependent inhibition of sulfiredoxin translation, maintaining the thioredoxin peroxidase activity of a peroxiredoxin and increasing the hydrogen peroxide resistance and replicative life span of Saccharomyces cerevisiae.
Copyright © 2011 Elsevier Inc. All rights reserved.