Translating a low-sugar diet into a longer life by maintaining thioredoxin peroxidase activity of a peroxiredoxin

Mol Cell. 2011 Sep 2;43(5):699-701. doi: 10.1016/j.molcel.2011.08.016.

Abstract

In this issue of Molecular Cell, Molin et al. (2011) reveal that caloric restriction alleviates PKA-dependent inhibition of sulfiredoxin translation, maintaining the thioredoxin peroxidase activity of a peroxiredoxin and increasing the hydrogen peroxide resistance and replicative life span of Saccharomyces cerevisiae.

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