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Cell. 2011 Sep 2;146(5):675-7. doi: 10.1016/j.cell.2011.08.006.

Basal synaptic transmission: astrocytes rule!

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1
Instituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid 28002, Spain.

Abstract

In this issue, Panatier et al. (2011) show that astrocytes detect synaptic activity induced by single action potentials and upregulate basal synaptic transmission through calcium-dependent mechanisms and purinergic signaling. These results demonstrate the relevance of astrocyte calcium in neurophysiology and confirm that astrocytes are actively involved in synaptic function.

PMID:
21884929
DOI:
10.1016/j.cell.2011.08.006
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