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Cardiovasc Ther. 2012 Aug;30(4):e183-8. doi: 10.1111/j.1755-5922.2011.00271.x. Epub 2011 Apr 1.

Ginsenoside Re: pharmacological effects on cardiovascular system.

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1
Section of Cardiology, Internal Medicine, JiShuiTan Hospital, Beijing 100035, China.

Abstract

Ginsenosides are the bioactive constituents of ginseng, a key herb in traditional Chinese medicine. As a single component of ginseng, ginsenoside Re (G-Re) belongs to the panaxatriol group. Many reports demonstrated that G-Re possesses the multifaceted beneficial pharmacological effects on cardiovascular system. G-Re has negative effect on cardiac contractility and autorhythmicity. It causes alternations in cardiac electrophysiological properties, which may account for its antiarrhythmic effect. In addition, G-Re also exerts antiischemic effect and induces angiogenic regeneration. In this review, we first outline the chemistry and the pharmacological effects of G-Re on the cardiovascular system.

[Indexed for MEDLINE]

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