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S Afr Med J. 1990 May 19;77(10):509-11.

Pseudomonas septicaemia after endoscopic retrograde cholangiopancreatography--an unresolved problem.

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Department of Surgery, Bacteriology, University of Cape Town.


Over a 6-month period 5 patients with obstructive jaundice developed Gram-negative septicaemia, all within 48 hours of undergoing endoscopic retrograde cholangiopancreatography. The sepsis proved fatal in 3 patients, despite prompt decompression of the obstructed biliary system. In all cases the organism responsible was Pseudomonas aeruginosa and the source of infection appeared to be a contaminated water-bottle attached to the endoscopic apparatus. This report highlights the importance of disinfection techniques and reviews the present situation in respect of antibiotic prophylaxis.

[Indexed for MEDLINE]

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