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RNA Biol. 2011 Sep-Oct;8(5):728-34. doi: 10.4161/rna.8.5.16324. Epub 2011 Sep 1.

The miR-10 microRNA precursor family.

Author information

1
Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark.

Abstract

The miR-10 microRNA precursor family encodes a group of short non-coding RNAs involved in gene regulation. The miR-10 family is highly conserved and has sparked the interest of many research groups because of the genomic localization in the vicinity of, coexpression with and regulation of the Hox gene developmental regulators. Here, we review the current knowledge of the evolution, physiological function and involvement in cancer of this family of microRNAs.

PMID:
21881411
PMCID:
PMC3256350
DOI:
10.4161/rna.8.5.16324
[Indexed for MEDLINE]
Free PMC Article

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