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Clin Infect Dis. 2011 Oct;53(7):e77-80. doi: 10.1093/cid/cir501. Epub 2011 Aug 31.

Treatment of parainfluenza 3 infection with DAS181 in a patient after allogeneic stem cell transplantation.

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1
Bone Marrow Transplant Unit, Massachusetts General Hospital, Boston, MA, USA. ychen6@partners.org

Abstract

Parainfluenza virus (PIV) can cause significant morbidity after allogeneic stem cell transplantation (SCT). We report the first use of inhaled DAS181 for PIV in an allogeneic SCT recipient. Symptoms, oxygenation, and pulmonary function tests improved. Nasopharyngeal samples showed a reduction in viral load. DAS181 should be systematically evaluated for severe PIV infection.

PMID:
21880586
DOI:
10.1093/cid/cir501
[Indexed for MEDLINE]
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