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Nutrition. 2012 Feb;28(2):154-9. doi: 10.1016/j.nut.2011.05.008. Epub 2011 Aug 26.

Effects of soybean peptide on immune function, brain function, and neurochemistry in healthy volunteers.

Author information

1
Research Institute, Xinjiang Medical University, Urumqi, People's Republic of China.

Abstract

OBJECTIVE:

Soybeans, an excellent source of dietary peptides, have beneficial effects on health. We investigated the effect of the soybean peptide on immune function, brain function, and neurochemistry in healthy volunteers.

METHODS:

Near-infrared spectroscopy (NIRS) was used to analyze brain cerebral blood flow. The A and DA levels in the serum were analyzed by ELISA kit. The total number of leukocytes was recorded with a standard counter. Flow cytometry was used to assess lymphocyte subset levels.

RESULTS:

Cell numbers were upregulated in the group that had fewer leukocytes but downregulated in the group with more leukocytes. For the lymphocyte-rich type, lymphocyte counts tended to decrease, accompanied by an increase in granulocyte numbers. For the granulocyte-rich type, granulocyte counts tended to increase, but lymphocyte counts also increased. The numbers of CD11b(+) cells and CD56(+) cells increased significantly. Soybean peptide decreased the adrenalin level in plasma but increased the level of dopamine. Near-infrared spectroscopy showed significant increases in the amplitudes of θ, α-2, and β-L frequency bands after the ingestion of peptides.

CONCLUSION:

Soybean peptides can modulate cellular immune systems, regulate neurotransmitters, and boost brain function.

PMID:
21872436
DOI:
10.1016/j.nut.2011.05.008
[Indexed for MEDLINE]

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