Format

Send to

Choose Destination
See comment in PubMed Commons below
Exp Eye Res. 2011 Oct;93(4):331-9. doi: 10.1016/j.exer.2011.08.007. Epub 2011 Aug 18.

Molecular genetics in glaucoma.

Author information

1
Center for Human Genetics, Duke University Medical Center, Durham, NC, USA.

Abstract

Glaucoma is a family of diseases whose pathology is defined by the progressive loss of retinal ganglion cells. Clinically, glaucoma presents as a distinctive optic neuropathy with associated visual field loss. Primary open-angle glaucoma (POAG), chronic angle-closure glaucoma (ACG), and exfoliation glaucoma (XFG) are the most prevalent forms of glaucoma globally and are the most common causes of glaucoma-related blindness worldwide. A host of genetic and environmental factors contribute to glaucoma phenotypes. This review examines the current status of genetic investigations of POAG, ACG, XFG, including the less common forms of glaucoma primary congenital glaucoma (PCG), the developmental glaucomas, and pigment dispersion glaucoma.

PMID:
21871452
PMCID:
PMC4293633
DOI:
10.1016/j.exer.2011.08.007
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center