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Clin Gastroenterol Hepatol. 2011 Dec;9(12):1044-9. doi: 10.1016/j.cgh.2011.08.014. Epub 2011 Aug 24.

Treating Clostridium difficile infection with fecal microbiota transplantation.

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1
St Luke's Infectious Disease Associates, Duluth, Minnesota, USA.

Abstract

Clostridium difficile infection is increasing in incidence, severity, and mortality. Treatment options are limited and appear to be losing efficacy. Recurrent disease is especially challenging; extended treatment with oral vancomycin is becoming increasingly common but is expensive. Fecal microbiota transplantation is safe, inexpensive, and effective; according to case and small series reports, about 90% of patients are cured. We discuss the rationale, methods, and use of fecal microbiota transplantation.

PMID:
21871249
PMCID:
PMC3223289
DOI:
10.1016/j.cgh.2011.08.014
[Indexed for MEDLINE]
Free PMC Article
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